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Molecular Mechanism of Thioflavin-T Binding to Amyloid Fibrils

Intense efforts to detect, diagnose, and analyze the kinetic and structural properties of amyloid fibrils have generated a powerful toolkit of amyloid-specific molecular probes. Since its first description in 1959, the fluorescent dye Thioflavin-T (ThT) has become among the most widely used “gold st...

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Autori principali: Biancalana, Matthew, Koide, Shohei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880406/
https://ncbi.nlm.nih.gov/pubmed/20399286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.04.001
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