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Oxidation of Plasma Cysteine/Cystine and GSH/GSSG Redox Potentials by Acetaminophen and Sulfur Amino Acid Insufficiency in Humans

Variations in plasma sulfur amino acid (SAA) pools are associated with disease risks, but little information is available about the factors affecting plasma SAA pools. Drug metabolism by glutathione (GSH) and sulfate conjugation can, in principle, represent a quantitatively important burden on SAA s...

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Bibliografiske detaljer
Main Authors: Mannery, Yanci O., Ziegler, Thomas R., Park, Youngja, Jones, Dean P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879932/
https://ncbi.nlm.nih.gov/pubmed/20207721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.166421
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