A carregar...
The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody forming cell and germinal center checkpoints
We have described a line of V(H) “knockin” mice termed HKIR in which the transgenic Igh locus partially encodes “dual reactive” anti-chromatin and anti-arsonate (Ars) BCRs. HKIR B cells termed canonical, expressing a particular Vκ light chain, evade central tolerance by down regulating BCR levels. C...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879885/ https://ncbi.nlm.nih.gov/pubmed/19828626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804215 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|