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Influence of Fas on the regulation of the response of an anti-nuclear antigen B cell clonotype to foreign antigen

A peripheral B cell tolerance checkpoint appears to be operative during the germinal center (GC) reaction. We previously showed that a transgenic BCR clonotype that is ‘dual reactive’ for the hapten arsonate (Ars) and nuclear auto-antigens is stimulated to enter the GC response via Ars immunization....

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Autori principali: Alabyev, Boris, Vuyyuru, Raja, Manser, Tim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542839/
https://ncbi.nlm.nih.gov/pubmed/18689725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn087
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