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Germinal center reutilization by newly activated B cells

Germinal centers (GCs) are specialized structures in which B lymphocytes undergo clonal expansion, class switch recombination, somatic hypermutation, and affinity maturation. Although these structures were previously thought to contain a limited number of isolated B cell clones, recent in vivo imagi...

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Detalhes bibliográficos
Main Authors: Schwickert, Tanja A., Alabyev, Boris, Manser, Tim, Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806468/
https://ncbi.nlm.nih.gov/pubmed/19934021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091225
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