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Integrin β4 Attenuates SHP-2 and MAPK Signaling and Reduces Human Lung Endothelial Inflammatory Responses
We previously identified the marked upregulation of integrin β4 in human lung endothelial cells (EC) treated with simvastatin, an HMG coA-reductase inhibitor with vascular-protective and anti-inflammatory properties in murine models of acute lung injury (ALI). We now investigate the role of integrin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879705/ https://ncbi.nlm.nih.gov/pubmed/20512931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22582 |
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