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Hsp70 ATPase Modulators as Therapeutics for Alzheimer’s and other Neurodegenerative Diseases

Neurodegenerative diseases caused by abnormal accumulation of the microtubule associated protein tau (MAPT, tau) are collectively called tauopathies. The most devastating tau related disorder is Alzheimer’s disease (AD). Molecular chaperones such as heat shock proteins (Hsp) have emerged as critical...

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Bibliografske podrobnosti
Main Authors: Jinwal, Umesh K., Koren, John, O’Leary, John C., Jones, Jeffrey R., Abisambra, Jose F., Dickey, Chad A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879647/
https://ncbi.nlm.nih.gov/pubmed/20523917
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