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The mineralization phenotype in Abcc6(−/−) mice is affected by Ggcx gene deficiency and genetic background – A model for pseudoxanthoma elasticum
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder characterized by ectopic mineralization of connective tissues, and shows considerable intra- and inter-familial phenotypic variability. PXE is caused by mutations in the ABCC6 gene, and targeted ablation of Abcc6 in mouse recapitulate...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879630/ https://ncbi.nlm.nih.gov/pubmed/19784827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0522-8 |
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