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Magnesium Carbonate‐Containing Phosphate Binder Prevents Connective Tissue Mineralization in Abcc6 (−/−) Mice–Potential for Treatment of Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a heritable disorder characterized by ectopic mineralization of connective tissues primarily in the skin, eyes, and the cardiovascular system. PXE is caused by mutations in the ABCC6 gene. While PXE is associated with considerable morbidity and mortality, there is c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Qiaoli, LaRusso, Jennifer, Grand‐Pierre, Alix E., Uitto, Jouni
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Inc 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005270/
https://ncbi.nlm.nih.gov/pubmed/20443931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00161.x
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