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Magnesium Carbonate‐Containing Phosphate Binder Prevents Connective Tissue Mineralization in Abcc6 (−/−) Mice–Potential for Treatment of Pseudoxanthoma Elasticum
Pseudoxanthoma elasticum (PXE) is a heritable disorder characterized by ectopic mineralization of connective tissues primarily in the skin, eyes, and the cardiovascular system. PXE is caused by mutations in the ABCC6 gene. While PXE is associated with considerable morbidity and mortality, there is c...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Inc
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3005270/ https://ncbi.nlm.nih.gov/pubmed/20443931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2009.00161.x |
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