Llwytho...
Understanding Microscopic Binding of Human Microsomal Prostaglandin E Synthase-1 (mPGES-1) Trimer with Substrate PGH(2) and Cofactor GSH: Insights from Computational Alanine Scanning and Site-directed Mutagenesis
Microsomal prostaglandin E synthase-1 (mPGES-1) is an essential enzyme involved in a variety of diseases and is the most promising target for the design of next-generation anti-inflammatory drugs. In order to establish a solid structural base, we recently developed a model of mPGES-1 trimer structur...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2010
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879598/ https://ncbi.nlm.nih.gov/pubmed/20369883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp100668y |
| Tagiau: |
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