Yüklüyor......
Understanding Microscopic Binding of Human Microsomal Prostaglandin E Synthase-1 (mPGES-1) Trimer with Substrate PGH(2) and Cofactor GSH: Insights from Computational Alanine Scanning and Site-directed Mutagenesis
Microsomal prostaglandin E synthase-1 (mPGES-1) is an essential enzyme involved in a variety of diseases and is the most promising target for the design of next-generation anti-inflammatory drugs. In order to establish a solid structural base, we recently developed a model of mPGES-1 trimer structur...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879598/ https://ncbi.nlm.nih.gov/pubmed/20369883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp100668y |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|