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Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity
POLN is a nuclear A-family DNA polymerase encoded in vertebrate genomes. POLN has unusual fidelity and DNA lesion bypass properties, including strong strand displacement activity, low fidelity favoring incorporation of T for template G and accurate translesion synthesis past a 5S-thymine glycol (5S-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879524/ https://ncbi.nlm.nih.gov/pubmed/20144948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq048 |
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