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Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model

BACKGROUND: Overexpression and abnormal accumulation of aggregated α-synuclein (αS) have been linked to Parkinson's disease (PD) and other synucleinopathies. αS can misfold and adopt a variety of morphologies but recent studies implicate oligomeric forms as the most cytotoxic species. Both gene...

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Autors principals: Wang, Min S, Boddapati, Shanta, Emadi, Sharareh, Sierks, Michael R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879277/
https://ncbi.nlm.nih.gov/pubmed/20433710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-57
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