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Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity
Alpha-synuclein (α-Syn) aggregation into oligomers and fibrils is associated with dopaminergic neuron loss occurring in Parkinson’s disease (PD) pathogenesis. Compounds that modulate α-Syn aggregation and interact with preformed fibrils/oligomers and convert them to less toxic species could have pro...
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| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919791/ https://ncbi.nlm.nih.gov/pubmed/27338805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28511 |
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