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Human α4β2 Nicotinic Acetylcholine Receptor as a Novel Target of Oligomeric α-Synuclein

Cigarette smoking is associated with a decreased incidence of Parkinson disease (PD) through unknown mechanisms. Interestingly, a decrease in the numbers of α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) in PD patients suggests an α4β2-nAChR-mediated cholinergic deficit in PD. Although oligome...

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Hlavní autoři: Liu, Qiang, Emadi, Sharareh, Shen, Jian-Xin, Sierks, Michael R., Wu, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577813/
https://ncbi.nlm.nih.gov/pubmed/23437071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055886
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