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Tg.2098 IS A MAJOR HUMAN THYROGLOBULIN T-CELL EPITOPE
An HLA-DR variant containing Arginine at position 74 of the DRβ1 chain confers a strong genetic susceptibility to autoimmune thyroid diseases (AITD), Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), while Glutamine at position DRβ1-74 is protective. We hypothesized that the DRβ1-Arg74 variant...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878895/ https://ncbi.nlm.nih.gov/pubmed/20303712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2010.01.004 |
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