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Interleukin (IL)-23 Receptor Is a Major Susceptibility Gene for Graves’ Ophthalmopathy: The IL-23/T-helper 17 Axis Extends to Thyroid Autoimmunity
Context: IL-23 and its receptor (IL-23R) guide T cells toward the T-helper 17 phenotype. IL-23R single nucleotide polymorphisms (SNPs) have been associated with several autoimmune diseases, including Crohn’s disease and rheumatoid arthritis. Objective: Our objective was to determine whether variants...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Endocrine Society
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266952/ https://ncbi.nlm.nih.gov/pubmed/18073300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-2190 |
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