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Interleukin (IL)-23 Receptor Is a Major Susceptibility Gene for Graves’ Ophthalmopathy: The IL-23/T-helper 17 Axis Extends to Thyroid Autoimmunity

Context: IL-23 and its receptor (IL-23R) guide T cells toward the T-helper 17 phenotype. IL-23R single nucleotide polymorphisms (SNPs) have been associated with several autoimmune diseases, including Crohn’s disease and rheumatoid arthritis. Objective: Our objective was to determine whether variants...

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Detalhes bibliográficos
Main Authors: Huber, Amanda K., Jacobson, Eric M., Jazdzewski, Krystian, Concepcion, Erlinda S., Tomer, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266952/
https://ncbi.nlm.nih.gov/pubmed/18073300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-2190
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