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Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

The secreted ligand Sonic Hedgehog (Shh) organizes the pattern of cellular differentiation in the ventral neural tube. For the five neuronal subtypes, increasing levels and durations of Shh signaling direct progenitors to progressively more ventral identities. Here we demonstrate that this mode of a...

詳細記述

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書誌詳細
主要な著者: Ribes, Vanessa, Balaskas, Nikolaos, Sasai, Noriaki, Cruz, Catarina, Dessaud, Eric, Cayuso, Jordi, Tozer, Samuel, Yang, Lin Lin, Novitch, Ben, Marti, Elisa, Briscoe, James
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878655/
https://ncbi.nlm.nih.gov/pubmed/20516201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.559910
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