Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

The secreted ligand Sonic Hedgehog (Shh) organizes the pattern of cellular differentiation in the ventral neural tube. For the five neuronal subtypes, increasing levels and durations of Shh signaling direct progenitors to progressively more ventral identities. Here we demonstrate that this mode of a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ribes, Vanessa, Balaskas, Nikolaos, Sasai, Noriaki, Cruz, Catarina, Dessaud, Eric, Cayuso, Jordi, Tozer, Samuel, Yang, Lin Lin, Novitch, Ben, Marti, Elisa, Briscoe, James
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2010
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878655/
https://ncbi.nlm.nih.gov/pubmed/20516201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.559910
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