Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

The secreted ligand Sonic Hedgehog (Shh) organizes the pattern of cellular differentiation in the ventral neural tube. For the five neuronal subtypes, increasing levels and durations of Shh signaling direct progenitors to progressively more ventral identities. Here we demonstrate that this mode of a...

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Bibliografische gegevens
Hoofdauteurs: Ribes, Vanessa, Balaskas, Nikolaos, Sasai, Noriaki, Cruz, Catarina, Dessaud, Eric, Cayuso, Jordi, Tozer, Samuel, Yang, Lin Lin, Novitch, Ben, Marti, Elisa, Briscoe, James
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878655/
https://ncbi.nlm.nih.gov/pubmed/20516201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.559910
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