Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog

Morphogens are secreted signalling molecules that act in a graded manner to control the pattern of cellular differentiation in developing tissues. An example is Sonic hedgehog (Shh), which acts in several developing vertebrate tissues, including the central nervous system, to provide positional info...

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Bibliographic Details
Main Authors: Dessaud, Eric, Ribes, Vanessa, Balaskas, Nikolaos, Yang, Lin Lin, Pierani, Alessandra, Kicheva, Anna, Novitch, Bennett G., Briscoe, James, Sasai, Noriaki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879390/
https://ncbi.nlm.nih.gov/pubmed/20532235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000382
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