Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

Secreted signals, known as morphogens, provide the positional information that organizes gene expression and cellular differentiation in many developing tissues. In the vertebrate neural tube, Sonic Hedgehog (Shh) acts as a morphogen to control the pattern of neuronal subtype specification. Using an...

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Hlavní autoři: Balaskas, Nikolaos, Ribeiro, Ana, Panovska, Jasmina, Dessaud, Eric, Sasai, Noriaki, Page, Karen M., Briscoe, James, Ribes, Vanessa
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267043/
https://ncbi.nlm.nih.gov/pubmed/22265416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.10.047
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