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Epithelial interleukin-4 receptor expression promotes colon tumor growth

Inflammatory mediators are of considerable interest as potential therapeutic targets in various cancers. Here we investigate whether interleukin (IL)-4 receptor alpha (IL4Rα), a component of the receptor complex for the T helper 2 cytokines IL4 and IL13, plays a role in colonic tumorigenesis. IL4Rα...

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Autors principals: Koller, Felicitas L., Hwang, Daniel G., Dozier, E.A., Fingleton, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878360/
https://ncbi.nlm.nih.gov/pubmed/20176658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq044
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