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IL-4 receptor ILR4α regulates metastatic colonization by mammary tumors through multiple signaling pathways
Interleukin-4 (IL4), a cytokine produced mainly by immune cells, may promote the growth of epithelial tumors by mediating increased proliferation and survival. Here, we show that the type II IL4 Receptor (IL4R) is expressed and activated in human breast cancer and mouse models of breast cancer. In m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134711/ https://ncbi.nlm.nih.gov/pubmed/24947041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0093 |
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