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Targeting IL4/IL4R for the treatment of epithelial cancer metastasis

While progress has been made in treating primary epithelial tumors, metastatic tumors remain largely incurable and still account for 85–90% of all cancer-related deaths. Interleukin-4 (IL4), a Th2 cytokine, and the IL4/IL4 receptor (IL4R) interaction have well defined roles in the immune system. Yet...

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Detalhes bibliográficos
Publicado no:Clin Exp Metastasis
Main Authors: Bankaitis, Katherine Venmar, Fingleton, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651701/
https://ncbi.nlm.nih.gov/pubmed/26385103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9747-9
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