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Lessons from immunology: IL4R directly promotes mammary tumor metastasis

Interleukin-4 (IL4), a Th2 cytokine, signals through IL4 receptors (IL4Rs) to regulate increased lymphocyte proliferation and survival. We have recently discovered that IL4 also promotes these phenotypes in mammary cancer cells expressing IL4Rs to enhance their metastatic ability. Targeting IL4/IL4R...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Venmar, Katherine T, Fingleton, Barbara
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292563/
https://ncbi.nlm.nih.gov/pubmed/25941616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.955373
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