Myeloperoxidase-dependent Inactivation of Surfactant Protein D in Vitro and in Vivo

Surfactant protein D (SP-D) plays diverse and important roles in innate immunity and pulmonary homeostasis. Neutrophils and myeloperoxidase (MPO) colocalized with SP-D in a murine bacterial pneumonia model of acute inflammation, suggesting that MPO-derived reactive species might alter the function o...

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Autores principales: Crouch, Erika C., Hirche, Tim O., Shao, Baohai, Boxio, Rachel, Wartelle, Julien, Benabid, Rym, McDonald, Barbara, Heinecke, Jay, Matalon, Sadis, Belaaouaj, Azzaq
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878025/
https://ncbi.nlm.nih.gov/pubmed/20228064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097048
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