Neutrophil Elastase Modulates Cytokine Expression: CONTRIBUTION TO HOST DEFENSE AGAINST PSEUDOMONAS AERUGINOSA-INDUCED PNEUMONIA

There is accumulating evidence that following bacterial infection, the massive recruitment and activation of the phagocytes, neutrophils, is accompanied with the extracellular release of active neutrophil elastase (NE), a potent serine protease. Using NE-deficient mice in a clinically relevant model...

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Detalhes bibliográficos
Main Authors: Benabid, Rym, Wartelle, Julien, Malleret, Laurette, Guyot, Nicolas, Gangloff, Sophie, Lebargy, François, Belaaouaj, Azzaq
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471768/
https://ncbi.nlm.nih.gov/pubmed/22927440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.361352
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