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Myeloperoxidase: An oxidative pathway for generating dysfunctional HDL
Accumulation of LDL-derived cholesterol by artery wall macrophages triggers atherosclerosis, the leading cause of cardiovascular disease. Conversely, HDL retards atherosclerosis by promoting cholesterol efflux from macrophages by the membrane-associated ATP-binding cassette transporter A1 (ABCA1) pa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838938/ https://ncbi.nlm.nih.gov/pubmed/20043647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9003775 |
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