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Myeloperoxidase: An oxidative pathway for generating dysfunctional HDL

Accumulation of LDL-derived cholesterol by artery wall macrophages triggers atherosclerosis, the leading cause of cardiovascular disease. Conversely, HDL retards atherosclerosis by promoting cholesterol efflux from macrophages by the membrane-associated ATP-binding cassette transporter A1 (ABCA1) pa...

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Autors principals: Shao, Baohai, Oda, Michael N., Oram, John F., Heinecke, Jay W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838938/
https://ncbi.nlm.nih.gov/pubmed/20043647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9003775
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