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Myeloperoxidase: An oxidative pathway for generating dysfunctional HDL

Accumulation of LDL-derived cholesterol by artery wall macrophages triggers atherosclerosis, the leading cause of cardiovascular disease. Conversely, HDL retards atherosclerosis by promoting cholesterol efflux from macrophages by the membrane-associated ATP-binding cassette transporter A1 (ABCA1) pa...

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Bibliografske podrobnosti
Main Authors: Shao, Baohai, Oda, Michael N., Oram, John F., Heinecke, Jay W.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838938/
https://ncbi.nlm.nih.gov/pubmed/20043647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9003775
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