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α-AP-2 Directs Myosin VI-dependent Endocytosis of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels in the Intestine

The actin motor myosin VI regulates endocytosis of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestine, but the endocytic adaptor linking CFTR to myosin VI is unknown. Dab2 (Disabled 2) is the binding partner for myosin VI, clathrin, and α-AP-2 and directs endocytosis of low...

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書誌詳細
主要な著者: Collaco, Anne, Jakab, Robert, Hegan, Peter, Mooseker, Mark, Ameen, Nadia
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878018/
https://ncbi.nlm.nih.gov/pubmed/20351096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127613
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