Revealing Novel Telomere Proteins Using in Vivo Cross-linking, Tandem Affinity Purification, and Label-free Quantitative LC-FTICR-MS

Telomeres are DNA-protein structures that protect chromosome ends from the actions of the DNA repair machinery. When telomeric integrity is compromised, genomic instability ensues. Considerable effort has focused on identification of telomere-binding proteins and elucidation of their functions. To d...

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Main Authors: Nittis, Thalia, Guittat, Lionel, LeDuc, Richard D., Dao, Ben, Duxin, Julien P., Rohrs, Henry, Townsend, R. Reid, Stewart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877976/
https://ncbi.nlm.nih.gov/pubmed/20097687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900490-MCP200
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