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TNF-α and IL-1β increase Ca(2+) leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes
Sepsis is associated with ventricular dysfunction and increased incidence of atrial and ventricular arrhythmia however the underlying pro-arrhythmic mechanisms are unknown. Serum levels of tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) are elevated during sepsis and affect Ca(2+) regula...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877880/ https://ncbi.nlm.nih.gov/pubmed/20227109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2010.02.002 |
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