Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage

The purpose of this study was to determine the sphingolipid (SL) profile in cells defective in autophagy protein ATG-7 and overall cell death after photodynamic therapy (PDT) with the photosensitizer Pc 4. MCF-7 human breast cancer cells with downregulated ATG-7 and their scrambled controls (Scr) we...

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Bibliografiska uppgifter
Huvudupphovsmän: Separovic, Duska, Kelekar, Ameeta, Nayak, Arun K., Tarca, Adi L., Hanada, Kentaro, Pierce, Jason S., Bielawski, Jacek
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877393/
https://ncbi.nlm.nih.gov/pubmed/19944062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.11.023
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