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Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage

The role o sphingomyelin synthase 1 (SMS1), the Golgi membrane isoform of the enzyme, in ceramide metabolism and apoptosis after photodamage with the photosensitizer Pc 4 (PDT) is unclear. In the present study, using electrospray ionization/double mass spectrometry, we show that in Jurkat cells over...

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Detalles Bibliográficos
Main Authors: Separovic, Duska, Hanada, Kentaro, Maitah, Ma'In Yehya Awad, Nagy, Biserka, Hang, Ivan, Tainsky, Michael A., Kraniak, Janice M., Bielawski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701614/
https://ncbi.nlm.nih.gov/pubmed/17467659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.04.095
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