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Mutation of Asn28 disrupts the dimerization and enzymatic activity of SARS 3CL(pro)

Coronaviruses are responsible for a significant proportion of annual respiratory and enteric infections in humans and other mammals. The most prominent of these viruses is the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) which causes acute respiratory and gastrointestinal infection in hu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barrila, Jennifer, Gabelli, Sandra B., Bacha, Usman, Amzel, L. Mario, Freire, Ernesto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877132/
https://ncbi.nlm.nih.gov/pubmed/20420403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1002585
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