Development of Broad‐Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CL(pro)

Coronaviruses comprise a large group of RNA viruses with diverse host specificity. The emergence of highly pathogenic strains like the SARS coronavirus (SARS‐CoV), and the discovery of two new coronaviruses, NL‐63 and HKU1, corroborates the high rate of mutation and recombination that have enabled t...

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Bibliographic Details
Main Authors: Bacha, Usman, Barrila, Jennifer, Gabelli, Sandra B., Kiso, Yoshiaki, Mario Amzel, L., Freire, Ernesto
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2008
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597651/
https://ncbi.nlm.nih.gov/pubmed/18611220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00679.x
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