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Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus
BACKGROUND: The adeno-associated virus (AAV) has many safety features that favor its use in the treatment of arthritic conditions; however, the conventional, single-stranded vector is inefficient for gene delivery to fibroblastic cells that primarily populate articular tissues. This has been attribu...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876984/ https://ncbi.nlm.nih.gov/pubmed/19384892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1334 |
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