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Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo
To understand the cellular and molecular events contributing to arthrofibrosis, we used an adenovirus to deliver and overexpress transforming growth factor-beta 1 (TGF-β1) cDNA (Ad.TGF-β1) in the knee joints of immunocompromised rats. Following delivery, animals were killed periodically, and joint t...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724510/ https://ncbi.nlm.nih.gov/pubmed/20697373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.145 |
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