Antibody-Mediated Protection against Mucosal Simian-Human Immunodeficiency Virus Challenge of Macaques Immunized with Alphavirus Replicon Particles and Boosted with Trimeric Envelope Glycoprotein in MF59 Adjuvant

We have previously shown that rhesus macaques were partially protected against high-dose intravenous challenge with simian-human immunodeficiency virus SHIV(SF162P4) following sequential immunization with alphavirus replicon particles (VRP) of a chimeric recombinant VEE/SIN alphavirus (derived from...

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Bibliografische gegevens
Hoofdauteurs: Barnett, Susan W., Burke, Brian, Sun, Yide, Kan, Elaine, Legg, Harold, Lian, Ying, Bost, Kristen, Zhou, Fengmin, Goodsell, Amanda, zur Megede, Jan, Polo, John, Donnelly, John, Ulmer, Jeffrey, Otten, Gillis R., Miller, Christopher J., Vajdy, Michael, Srivastava, Indresh K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876657/
https://ncbi.nlm.nih.gov/pubmed/20392857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02533-09
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