Antibody-Mediated Protection against Mucosal Simian-Human Immunodeficiency Virus Challenge of Macaques Immunized with Alphavirus Replicon Particles and Boosted with Trimeric Envelope Glycoprotein in MF59 Adjuvant

We have previously shown that rhesus macaques were partially protected against high-dose intravenous challenge with simian-human immunodeficiency virus SHIV(SF162P4) following sequential immunization with alphavirus replicon particles (VRP) of a chimeric recombinant VEE/SIN alphavirus (derived from...

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Главные авторы: Barnett, Susan W., Burke, Brian, Sun, Yide, Kan, Elaine, Legg, Harold, Lian, Ying, Bost, Kristen, Zhou, Fengmin, Goodsell, Amanda, zur Megede, Jan, Polo, John, Donnelly, John, Ulmer, Jeffrey, Otten, Gillis R., Miller, Christopher J., Vajdy, Michael, Srivastava, Indresh K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876657/
https://ncbi.nlm.nih.gov/pubmed/20392857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02533-09
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