Antibody-Mediated Protection against Mucosal Simian-Human Immunodeficiency Virus Challenge of Macaques Immunized with Alphavirus Replicon Particles and Boosted with Trimeric Envelope Glycoprotein in MF59 Adjuvant

We have previously shown that rhesus macaques were partially protected against high-dose intravenous challenge with simian-human immunodeficiency virus SHIV(SF162P4) following sequential immunization with alphavirus replicon particles (VRP) of a chimeric recombinant VEE/SIN alphavirus (derived from...

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Detalhes bibliográficos
Main Authors: Barnett, Susan W., Burke, Brian, Sun, Yide, Kan, Elaine, Legg, Harold, Lian, Ying, Bost, Kristen, Zhou, Fengmin, Goodsell, Amanda, zur Megede, Jan, Polo, John, Donnelly, John, Ulmer, Jeffrey, Otten, Gillis R., Miller, Christopher J., Vajdy, Michael, Srivastava, Indresh K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876657/
https://ncbi.nlm.nih.gov/pubmed/20392857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02533-09
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