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Efficient Generation of Mucosal and Systemic Antigen-Specific CD8(+) T-Cell Responses following Pulmonary DNA Immunization

Although mucosal CD8(+) T-cell responses are important in combating mucosal infections, the generation of such immune responses by vaccination remains problematic. In the present study, we evaluated the ability of plasmid DNA to induce local and systemic antigen-specific CD8(+) T-cell responses afte...

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書誌詳細
主要な著者: Bivas-Benita, Maytal, Bar, Liat, Gillard, Geoffrey O., Kaufman, David R., Simmons, Nathaniel L., Hovav, Avi-Hai, Letvin, Norman L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876582/
https://ncbi.nlm.nih.gov/pubmed/20335249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-09
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