Efficient Generation of Mucosal and Systemic Antigen-Specific CD8(+) T-Cell Responses following Pulmonary DNA Immunization

Although mucosal CD8(+) T-cell responses are important in combating mucosal infections, the generation of such immune responses by vaccination remains problematic. In the present study, we evaluated the ability of plasmid DNA to induce local and systemic antigen-specific CD8(+) T-cell responses afte...

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Bibliografiska uppgifter
Huvudupphovsmän: Bivas-Benita, Maytal, Bar, Liat, Gillard, Geoffrey O., Kaufman, David R., Simmons, Nathaniel L., Hovav, Avi-Hai, Letvin, Norman L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876582/
https://ncbi.nlm.nih.gov/pubmed/20335249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-09
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