Efficient Generation of Mucosal and Systemic Antigen-Specific CD8(+) T-Cell Responses following Pulmonary DNA Immunization

Although mucosal CD8(+) T-cell responses are important in combating mucosal infections, the generation of such immune responses by vaccination remains problematic. In the present study, we evaluated the ability of plasmid DNA to induce local and systemic antigen-specific CD8(+) T-cell responses afte...

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Detaylı Bibliyografya
Asıl Yazarlar: Bivas-Benita, Maytal, Bar, Liat, Gillard, Geoffrey O., Kaufman, David R., Simmons, Nathaniel L., Hovav, Avi-Hai, Letvin, Norman L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Vaccines and Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876582/
https://ncbi.nlm.nih.gov/pubmed/20335249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-09
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