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Efficient Generation of Mucosal and Systemic Antigen-Specific CD8(+) T-Cell Responses following Pulmonary DNA Immunization
Although mucosal CD8(+) T-cell responses are important in combating mucosal infections, the generation of such immune responses by vaccination remains problematic. In the present study, we evaluated the ability of plasmid DNA to induce local and systemic antigen-specific CD8(+) T-cell responses afte...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876582/ https://ncbi.nlm.nih.gov/pubmed/20335249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-09 |
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