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Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8(+) T Lymphocytes

The duration of Ag expression in vivo has been reported to have a minimal impact on both the magnitude and kinetics of contraction of a pathogen-induced CD8(+) T cell response. In this study, we controlled the duration of Ag expression by excising the ear pinnae following intradermal ear pinnae DNA...

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Detalhes bibliográficos
Main Authors: Hovav, Avi-Hai, Panas, Michael W., Rahman, Shaila, Sircar, Piya, Gillard, Geoffrey, Cayabyab, Mark J., Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190620/
https://ncbi.nlm.nih.gov/pubmed/17982062
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