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Effect of Vicriviroc on the QT/Corrected QT Interval and Central Nervous System in Healthy Subjects
Vicriviroc is a CCR5 antagonist in clinical development for the treatment of HIV-1. Two phase I studies were conducted to assess the safety of vicriviroc. One study characterized the drug's potential to prolong the QT/corrected QT (QTc) interval and to induce arrhythmia. In this partially blind...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876383/ https://ncbi.nlm.nih.gov/pubmed/20350942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01447-09 |
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