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Effect of Vicriviroc on the QT/Corrected QT Interval and Central Nervous System in Healthy Subjects

Vicriviroc is a CCR5 antagonist in clinical development for the treatment of HIV-1. Two phase I studies were conducted to assess the safety of vicriviroc. One study characterized the drug's potential to prolong the QT/corrected QT (QTc) interval and to induce arrhythmia. In this partially blind...

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Detalhes bibliográficos
Main Authors: O'Mara, Edward, Kasserra, Claudia, Huddlestone, John Robert, Wan, Yuntao, Soni, Peter, Caceres, Maria, Medlock, Matthew, Morrison, Royce, Devinsky, Orrin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876383/
https://ncbi.nlm.nih.gov/pubmed/20350942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01447-09
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