Carregant...

The Identification and Biochemical Characterization of Drug-Like Compounds that Inhibit Botulinum Neurotoxin Serotype A Endopeptidase Activity

A robust, high throughput, two-tiered assay for screening small molecule inhibitors against botulinum neurotoxin serotype A was developed and employed to screen 16,544 compounds. Thirty-four compounds were identified as potent hits employing the first-tier assay. Subsequently, nine were confirmed as...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Cai, Shuowei, Lindo, Paul, Park, Jong-Beak, Vasa, Kruti, Singh, Bal Ram
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876331/
https://ncbi.nlm.nih.gov/pubmed/20003913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2009.11.017
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!