New Therapeutic and Biomarker Discovery for Peripheral Diabetic Neuropathy: PARP Inhibitor, Nitrotyrosine, and Tumor Necrosis Factor-α

This study evaluated poly(ADP-ribose) polymerase (PARP) inhibition as a new therapeutic approach for peripheral diabetic neuropathy using clinically relevant animal model and endpoints, and nitrotyrosine (NT), TNF-α, and nitrite/nitrate as potential biomarkers of the disease. Control and streptozoto...

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Detalhes bibliográficos
Main Authors: Drel, Viktor R., Lupachyk, Sergey, Shevalye, Hanna, Vareniuk, Igor, Xu, Weizheng, Zhang, Jie, Delamere, Nicholas A., Shahidullah, Mohammad, Slusher, Barbara, Obrosova, Irina G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875829/
https://ncbi.nlm.nih.gov/pubmed/20357221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1342
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