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Expression Profiling of Nuclear Receptors in the NCI60 Cancer Cell Panel Reveals Receptor-Drug and Receptor-Gene Interactions

We profiled the expression of the 48 human nuclear receptors (NRs) by quantitative RT-PCR in 51 human cancer cell lines of the NCI60 collection derived from nine different tissues. NR mRNA expression accurately classified melanoma, colon, and renal cancers, whereas lung, breast, prostate, central ne...

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Autors principals: Holbeck, Susan, Chang, Jianjun, Best, Anne M., Bookout, Angie L., Mangelsdorf, David J., Martinez, Elisabeth D.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875807/
https://ncbi.nlm.nih.gov/pubmed/20375240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0040
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