Expression Profiling of Nuclear Receptors in the NCI60 Cancer Cell Panel Reveals Receptor-Drug and Receptor-Gene Interactions

We profiled the expression of the 48 human nuclear receptors (NRs) by quantitative RT-PCR in 51 human cancer cell lines of the NCI60 collection derived from nine different tissues. NR mRNA expression accurately classified melanoma, colon, and renal cancers, whereas lung, breast, prostate, central ne...

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Huvudupphovsmän: Holbeck, Susan, Chang, Jianjun, Best, Anne M., Bookout, Angie L., Mangelsdorf, David J., Martinez, Elisabeth D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Endocrine Society 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875807/
https://ncbi.nlm.nih.gov/pubmed/20375240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0040
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