c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis

INTRODUCTION: Tyrosine kinases are key mediators of multiple signaling pathways implicated in rheumatoid arthritis (RA). We previously demonstrated that imatinib mesylate--a Food and Drug Administration (FDA)-approved, antineoplastic drug that potently inhibits the tyrosine kinases Abl, c-Kit, plate...

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Detalhes bibliográficos
Main Authors: Paniagua, Ricardo T, Chang, Anna, Mariano, Melissa M, Stein, Emily A, Wang, Qian, Lindstrom, Tamsin M, Sharpe, Orr, Roscow, Claire, Ho, Peggy P, Lee, David M, Robinson, William H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875666/
https://ncbi.nlm.nih.gov/pubmed/20181277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2940
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