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c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis
INTRODUCTION: Tyrosine kinases are key mediators of multiple signaling pathways implicated in rheumatoid arthritis (RA). We previously demonstrated that imatinib mesylate--a Food and Drug Administration (FDA)-approved, antineoplastic drug that potently inhibits the tyrosine kinases Abl, c-Kit, plate...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875666/ https://ncbi.nlm.nih.gov/pubmed/20181277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2940 |
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